七十年代，城市知青馬杰（文章 飾）來到西北某農(nóng)村插隊，被村里漂亮種驢——黑六的叫聲吸引。馬杰嫌黑六不讓他騎，某次工傷在診所縫針時偷了麻醉劑打給黑六，隊長大蓮（岳紅 飾）以為黑六生病，心急如焚。馬杰奇跡般地“治愈”了黑六，贏得大蓮和隊里的信任，成為牲口飼養(yǎng)員。馬杰一邊喂驢，一邊偷偷與村里的女青年彩鳳（白靜 飾）相戀。與此同時，馬杰對黑六只配種不干活的特殊待遇愈發(fā)不滿，并對大蓮“驢比人值錢”的論調(diào)暗自氣憤，發(fā)泄中竟打壞了黑六的“命根子”。無法配種也不能干活的黑六被馬杰宰殺，卻沒曾想黑六的弟弟，毛驢黑七，從此與馬杰不共戴天。人與驢的斗爭愈演愈烈。
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